The global pandemic has significantly transformed the existing system of international relations, dividing and opposing its structures to each other. The processes of globalization have been suspended due to the large-scale outbreak of COVID-19, that is why regionalization is taking place instead of globalization nowadays. In addition, the pandemic has affected both the economic development of countries and the functioning of transnational corporations. The article considers the problematic situations faced by TNCs during the pandemic. Taking into account structural changes, significant global actors have intensified their efforts to strengthen their positions in the Asia-Pacific region, which will occupy a central place in political and economic processes in the nearest future. This article analyzes the activities of transnational corporations in Southeast Asia. The authors of the article examine the influence of transnational corporations on the formation and promotion of the ASEAN institutional policy applied in the region. The paper presents assessment of the work of TNCs in the region after the signing and ratification of the comprehensive regional economic partnership. The authors consider the impact of regional states on the ASEAN economy by encouraging the development of domestic TNCs in the member countries of the organization. The results of this study make it possible to identify the features of the functioning of foreign TNCs in ASEAN, as well as to define aspects that contribute to reducing the Association's dependence on foreign influence.
